Institutional Review Board

IRB Acronyms

Acronym Definition
AAHRPP Association for the Accreditation of Human Research Protections Programs (NIH funds both regional centers and a national center: http://www.nattc.org/
ACRP Association of Clinical Research Professionals
ADR Adverse Drug Reaction
AE Adverse Event
ARENA Applied Research Ethics National Association
ATTC Addiction Technology Transfer Center
CE Covered Entity
CFR Code of Federal Regulations
CIM Certified IRB Manager
CIP Certified IRB Professional
COC Certificate of Confidentiality
COI Conflict of Interest
CPA Cooperative Project Assurance
CR Common Rule
CRA Clinical Research Associate
CRF Case Report Form
CRO Clinical Research Organization/Contract Research Organization
CRC Clinical Research Coordinator
DHEW Department of Health, Education and Welfare (no longer exists)
DHHS Department of Health and Human Services (replaced DHEW)
DIA Drug Information Association
DMC Data Monitoring Committee
DSMB Data Safety Monitoring Board
ECOG Eastern Co-operative Oncology Group (This is the largest multi-center group doing cancer clinical trials: http://ecog.dfci.harvard.edu/
EQUIC Enhancing Quality of Informed Consent
FDA Food and Drug Administration
FWA Federal Wide Assurance
GCP Good Clinical Practice
GOG Gynecologic Oncology Group
HDE Humanitarian Device Exemption http://www.fda.gov/orphan/
HIPAA Health Insurance Portability and Accountability Act
HMO Health Maintenance Organization
HPA Human Protections Administrator
HRP Human Research Protections
HSR Health Services Research
HUD Humanitarian Use Device
IACUC Institutional Animal Care and Use Committee: http://www.iacuc.org/
IB Investigator's Brochure
IBC Institutional Biohazard Committee
ICF Individual Consent Form or Institutional Consent Form
ICH International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals
IDE Investigational Device Exemption
IEC Institutional Ethics Committee/Independent Ethics Committee
IND Investigational New Drug
IRB Institutional Review Board
JCAHO Joint Commission on Accreditation of Healthcare Organizations
JIT Just in Time (procedure)
LCME Liaison Committee for Medical Education (This is the American Assoc. of Medical Colleges accrediting authority for U.S. programs leading to the M.D. degree)
LTF Subjects Lost to Follow-up Subjects (This is a funding mechanism for funding research scientists run by the International Human Frontier Science Program Organization: www.hfsp.org/how/faq_LTF.htm
MPA Multiple Projects Assurance
MSO Medical Staff Office
NAIM National Association of IRB Managers
NCPHSBBR National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research
NBAC National Bioethics Advisory Commission
NCQA National Committee for Quality Assurance
NDA New Drug Application
NIH National Institute of Health
NHRPAC National Human Research Protections Advisory Committee
NIA Nonaffiliated Investigator Agreement
NSR Non significant Risk
NRMI National Registry of Myocardial Infarction
OHRP Office of Human Research Protections (formerly OPRR)
OPRR Office of Protection from Research Risks
ORA Office of Regulatory Affairs
ORCA Office of Research Compliance & Assurance
ORI Office of Research Integrity
OSHA Occupational Safety and Health Administration
PI Principal Investigator
PHI Private Healthcare Information/Public Health Information/Protected Health Info.
PHS Public Health Service (USPHS United States Public Health Service)
PMA Pre Market Approval
POG Pediatric Oncology Group
PRIMR Public Responsibility in Medicine and Research
QA Quality Assurance
QC Quality Control
QI Quality Improvement
RAPS Regulatory Affairs Professionals Society
RCO Regulatory Compliance Officer
REB Research Ethics Board
RCT Randomized Control Trial
RCR Responsible Conduct of Research
RTOG Radiation Therapy Oncology Group www.rtog.org
SAE Serious Adverse Events
SAP Suspect Adverse Reaction
SMO Site Management Organization
SOP Standard Operating Procedure
SPA Single Project Assurance
SR Safety Report/Significant Risk
SRO Sponsored Research Office
SWOG South West Oncology Group (Another NIIH/NCI supported multi-center cancer clinical trials group: www.swog.org
VA Veteran's Affairs
VPR Vice President for Research
WMA World Medical Association